Use of antipsychotics - an analysis of lifetime treatment in 66 patients with psychoses.

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Use of antipsychotics - an analysis of lifetime treatment in 66 patients with psychoses.

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Publication Article, peer reviewed scientific
Title Use of antipsychotics - an analysis of lifetime treatment in 66 patients with psychoses.
Author(s) Jönsson, Erik G ; Saetre, Peter ; Vares, Maria ; Stralin, Pontus ; Levander, Sten ; Lindström, Eva
Date 2012
English abstract
Only a minority of patients treated with antipsychotics in clinical studies continue their treatments throughout a longer study period. Few studies address this issue from a lifetime perspective. In this naturalistic study, we aimed at analysing the prescription pattern of antipsychotic drugs among a sample of Swedish patients with a diagnosis of psychotic illness, from the first contact with psychiatry (typically between 1973 and 1997) until the last written note in the case history documents. A retrospective descriptive analysis was performed of all case history data of 66 patients diagnosed with schizophrenia or related psychotic disorders. Patients with schizophrenia were prescribed antipsychotic medication more than 90% of the time. Each patient generally had been prescribed several (up to 16) different antipsychotic drugs and a quarter of the patients had been prescribed two or more antipsychotics for a third of their prescription time. Patients with psychosis were exposed to a cumulatively growing number of antipsychotics. Various factors, including clinician and patient expectations, and specific strengths and limitations of available antipsychotics may account for frequent medication changes over time.
DOI http://dx.doi.org/10.1016/j.psychres.2010.10.027 (link to publisher's fulltext)
Publisher Elsevier
Host/Issue Psychiatry Research;1-2
Volume 187
ISSN 0165-1781
Pages 80-88
Language eng (iso)
Subject(s) antipsychotic drugs
schizophrenia
retrospective
poly-pharmacy
lifetime
Medicine
Research Subject Categories::MEDICINE
Handle http://hdl.handle.net/2043/13812 (link to this page)

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