Use of antipsychotics - an analysis of lifetime treatment in 66 patients with psychoses.

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Use of antipsychotics - an analysis of lifetime treatment in 66 patients with psychoses.

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dc.contributor.author Jönsson, Erik G
dc.contributor.author Saetre, Peter
dc.contributor.author Vares, Maria
dc.contributor.author Stralin, Pontus
dc.contributor.author Levander, Sten
dc.contributor.author Lindström, Eva
dc.date.accessioned 2012-06-18T10:17:40Z
dc.date.available 2012-06-18T10:17:40Z
dc.date.issued 2012 en_US
dc.identifier.citation 80-88 en_US
dc.identifier.issn 0165-1781
dc.identifier.uri http://hdl.handle.net/2043/13812
dc.description.abstract Only a minority of patients treated with antipsychotics in clinical studies continue their treatments throughout a longer study period. Few studies address this issue from a lifetime perspective. In this naturalistic study, we aimed at analysing the prescription pattern of antipsychotic drugs among a sample of Swedish patients with a diagnosis of psychotic illness, from the first contact with psychiatry (typically between 1973 and 1997) until the last written note in the case history documents. A retrospective descriptive analysis was performed of all case history data of 66 patients diagnosed with schizophrenia or related psychotic disorders. Patients with schizophrenia were prescribed antipsychotic medication more than 90% of the time. Each patient generally had been prescribed several (up to 16) different antipsychotic drugs and a quarter of the patients had been prescribed two or more antipsychotics for a third of their prescription time. Patients with psychosis were exposed to a cumulatively growing number of antipsychotics. Various factors, including clinician and patient expectations, and specific strengths and limitations of available antipsychotics may account for frequent medication changes over time. en_US
dc.language.iso eng en_US
dc.publisher Elsevier
dc.subject antipsychotic drugs en_US
dc.subject schizophrenia en_US
dc.subject retrospective en_US
dc.subject poly-pharmacy en_US
dc.subject lifetime en_US
dc.subject.classification Medicine en_US
dc.title Use of antipsychotics - an analysis of lifetime treatment in 66 patients with psychoses. en_US
dc.type Article, peer reviewed scientific en_US
dc.contributor.department Malmö University. Faculty of Health and Society en
dc.identifier.doi http://dx.doi.org/10.1016/j.psychres.2010.10.027 en_US
dc.subject.srsc Research Subject Categories::MEDICINE en_US
dc.relation.ispartofpublication Psychiatry Research;1-2
dc.relation.ispartofpublicationvolume 187 en_US
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