Concomitant medication of psychoses in a lifetime perspective

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Concomitant medication of psychoses in a lifetime perspective

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dc.contributor.author Vares, Maria
dc.contributor.author Saetre, Peter
dc.contributor.author Strålin, Pontus
dc.contributor.author Levander, Sten
dc.contributor.author Lindström, Eva
dc.contributor.author Jönsson, Erik G
dc.date.accessioned 2012-06-28T07:22:01Z
dc.date.available 2012-06-28T07:22:01Z
dc.date.issued 2011 en_US
dc.identifier.citation 322-331 en_US
dc.identifier.issn 1099-1077 en_US
dc.identifier.uri http://hdl.handle.net/2043/13874
dc.description.abstract OBJECTIVE: Patients treated with antipsychotic drugs often receive concomitant psychotropic compounds. Few studies address this issue from a lifetime perspective. Here, an analysis is presented of the prescription pattern of such concomitant medication from the first contact with psychiatry until the last written note in the case history documents, in patients with a diagnosis of psychotic illness. METHODS: A retrospective descriptive analysis of all case history data of 66 patients diagnosed with schizophrenia or schizophrenia-like psychotic disorders. RESULTS: Benzodiazepines and benzodiazepine-related anxiolytic drugs had been prescribed to 95% of the patients, other anxiolytics, sedatives or hypnotic drugs to 61%, anti-parkinsonism drugs to 86%, and antidepressants to 56% of the patients. However, lifetime doses were small and most of the time patients had no concomitant medication. The prescribed lifetime dose of anti-parkinsonism drugs was associated with that of prescribed first-generation but not second-generation antipsychotics. CONCLUSIONS: Most psychosis patients are sometimes treated with concomitant drugs but mainly over short periods. Lifetime concomitant add-on medication at the individual patient level is variable and complex but not extensive. en_US
dc.language.iso eng en_US
dc.publisher John Wiley and Sons en_US
dc.subject antipsychotic drugs en_US
dc.subject concomitant medication en_US
dc.subject schizophrenia en_US
dc.subject retrospective en_US
dc.subject poly-pharmacy en_US
dc.subject lifetime en_US
dc.subject.classification Medicine en_US
dc.title Concomitant medication of psychoses in a lifetime perspective en_US
dc.type Article, peer reviewed scientific en_US
dc.contributor.department Malmö University. Faculty of Health and Society en
dc.identifier.doi http://dx.doi.org/10.1002/hup.1209 en_US
dc.subject.srsc Research Subject Categories::MEDICINE en_US
dc.relation.ispartofpublication Human Psychopharmacology: Clinical and Experimental;4-5
dc.relation.ispartofpublicationvolume 26 en_US
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