Factors associated with changes in quality of life in patients undergoing allogeneic haematopoietic stem cell transplantation.

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Factors associated with changes in quality of life in patients undergoing allogeneic haematopoietic stem cell transplantation.

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dc.contributor.author Kisch, Annika
dc.contributor.author Lenhoff, Stig
dc.contributor.author Zdravkovic, Slobodan
dc.contributor.author Bolmsjö, Ingrid
dc.date.accessioned 2012-09-26T12:06:06Z
dc.date.available 2012-09-26T12:06:06Z
dc.date.issued 2012 en_US
dc.identifier.citation 735-46 en_US
dc.identifier.issn 1365-2354 en_US
dc.identifier.uri http://hdl.handle.net/2043/14150
dc.description.abstract Factors associated with changes in quality of life in patients undergoing allogeneic haematopoietic stem cell transplantation It is well known that patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT) experience changes in quality of life. We investigated factors associated with quality of life changes in adult HSCT patients. The Functional Assessment of Cancer Therapy - Bone Marrow Transplantation (FACT-BMT) scale, supplemented with the Functional Assessment of Chronic Illness Therapy - Spiritual Well-being (FACIT-Sp) subscale, was administered on three occasions, immediately before transplantation, 100 days and 12 months after transplantation. Analyses of nine selected factors were made where changes in quality of life were found. Seventy-five patients were included and 40 of these completed the study. Emotional well-being was found to improve between the baseline and 100 days, while all other dimensions deteriorated, including overall quality of life. Physical and social/family well-being deteriorated between the baseline and the 12-month follow-up, while emotional well-being improved. The main factors associated with deteriorating quality of life over time were found to be significant infections, female gender and transplantation with stem cells from a sibling donor. In our further studies we aim to focus on the relationships between patients and sibling donors in order to improve the care. Careful attention must be paid to continuous adequate information during the transplantation procedure. en_US
dc.language.iso eng en_US
dc.publisher Blackwell Publishing en_US
dc.subject quality of life en_US
dc.subject FACT-BMT en_US
dc.subject FACIT-Sp en_US
dc.subject allogeneic haematopoietic stem cell transplantation en_US
dc.subject sibling donor en_US
dc.subject.classification Medicine en_US
dc.title Factors associated with changes in quality of life in patients undergoing allogeneic haematopoietic stem cell transplantation. en_US
dc.type Article, peer reviewed scientific en_US
dc.contributor.department Malmö University. Faculty of Health and Society en
dc.identifier.doi http://dx.doi.org/10.1111/j.1365-2354.2012.01354.x en_US
dc.subject.srsc Research Subject Categories::MEDICINE en_US
dc.relation.ispartofpublication European Journal of Cancer Care;6
dc.relation.ispartofpublicationvolume 21
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Quality of life study

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