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  • 1.
    Gari, Hala
    et al.
    Malmö högskola, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
    Rembiesa, Jadwiga
    Malmö högskola, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
    Masilionis, Ignas
    Malmö högskola, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
    Vreda, Naida
    Malmö högskola, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
    Svensson, Birgitta
    Sund, Torbjörn
    Hansson, Henri
    Morén, Anna Karin
    Sjöö, Malin
    Wahlgren, Marie
    Engblom, Johan
    Malmö högskola, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
    Ruzgas, Tautgirdas
    Malmö högskola, Faculty of Health and Society (HS), Department of Biomedical Science (BMV).
    Amperometric in vitro monitoring of penetration through skin membrane2015In: Electroanalysis, ISSN 1040-0397, E-ISSN 1521-4109, Vol. 27, no 1, p. 111-117Article in journal (Refereed)
    Abstract [en]

    The aim of this study was to demonstrate that penetration of quercetin, hydrogen peroxide and ascorbic acid through skin membranes can be monitored amperometrically. Skin membrane was fixed on the top of chemically modified electrodes and penetration of the appropriate compound was registered as electrode current. The methodology allows the study of penetration from solution as well as from pharmaceutical creams. From realtime measurements of electrode current, fluxes and diffusion coefficients of mentioned compounds in skin membranes have been estimated.

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