Friction Force Spectroscopy as a Tool to Study the Strength and Structure of Salivary Films

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Friction Force Spectroscopy as a Tool to Study the Strength and Structure of Salivary Films

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Publication Article, peer reviewed scientific
Title Friction Force Spectroscopy as a Tool to Study the Strength and Structure of Salivary Films
Author(s) Sotres, Javier ; Lindh, Liselott ; Arnebrant, Thomas
Date 2011
English abstract
In this work, we employ atomic force microscopy based friction force spectroscopy to study the strength and structure of salivary films. Specifically, films formed on model hydrophobic (methylated silica) and hydrophilic (clean silica) substrata have been studied in water at pHs in the range 3.3–7. Results reveal that films formed on both types of substrata can be described in terms of two different fractions, with only one of them being able to diffuse along the underlying substrata. We also show how the protective function of the films is reduced when the pH of the surrounding medium is lowered. Specifically, lowering of pH causes desorption of some components of the films formed on hydrophobic methylated surfaces, leading to weaker layers. In contrast, at low pHs, saliva no longer forms a layer on hydrophilic silica surfaces. Instead, an inhomogeneous distribution of amorphous aggregates is observed. Our data also suggest that hydrophobic materials in the oral cavity might be more easily cleaned from adsorbed salivary films. Finally, reproducible differences are observed in results from experiments on films from different individuals, validating the technique as a tool for clinical diagnosis of the resistance to erosion of salivary films.
DOI http://dx.doi.org/10.1021/la202870c (link to publisher's fulltext)
Publisher American Chemical Society
Host/Issue Langmuir;22
Volume 27
ISSN 0743-7463
Pages 13692-13700
Language eng (iso)
Subject(s) Sciences
Research Subject Categories::NATURAL SCIENCES
Handle http://hdl.handle.net/2043/12642 (link to this page)

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