Chitosan Nanoparticles Affect the Acid Tolerance Response in Adhered Cells of Streptococcus mutans

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Chitosan Nanoparticles Affect the Acid Tolerance Response in Adhered Cells of Streptococcus mutans

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Publication Article, peer reviewed scientific
Title Chitosan Nanoparticles Affect the Acid Tolerance Response in Adhered Cells of Streptococcus mutans
Author(s) Neilands, Jessica ; Sutherland, Donald ; Resin, Anton ; Wejse, Peter Langborn ; Chávez de Paz, Luis Eduardo
Date 2011
English abstract
In this study we evaluated the effect of chitosan nanoparticles on the acid tolerance response (ATR) of adhered Streptococcus mutans. An ATR was induced by exposing S. mutans to pH 5.5 for 2 h and confirmed by exposing the acid-adapted cells to pH 3.5 for 30 min, with the majority of cells appearing viable according to the LIVE/DEAD® technique. However, when chitosan nanoparticles were present during the exposure to pH 5.5, no ATR occurred as most cells appeared dead after the pH 3.5 shock. We conclude that the chitosan nanoparticles tested had the ability to hinder ATR induction in adhered S. mutans.
DOI http://dx.doi.org/10.1159/000331206 (link to publisher's fulltext)
Publisher S. Karger AG, Basel
Host/Issue Caries Research;6
Volume 45
Pages 501-505
Language eng (iso)
Subject(s) Acid tolerance
Biofilms
Chitosan
Nanoparticles
Streptococcus mutans
Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/12957 (link to this page)

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