Treatment satisfaction with insulin glargine in patients with diabetes mellitus in a university hospital clinic in Sweden

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Treatment satisfaction with insulin glargine in patients with diabetes mellitus in a university hospital clinic in Sweden

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Publication Article, peer reviewed scientific
Title Treatment satisfaction with insulin glargine in patients with diabetes mellitus in a university hospital clinic in Sweden
Author(s) Annersten Gershater, Magdalena ; Frid, Anders ; Apelqvist, Jan
Date 2009
English abstract
Background: Few studies evaluate patients' perspectives when a new drug is introduced to treat chronic diseases such as diabetes mellitus. The clinical role of a new insulin treatment, in terms of the relationship between higher cost and better treatment outcomes (as defined from the patient perspective) has been discussed. We sought to explore patient satisfaction with a new insulin treatment (insulin glargine). At its launch in 2002/3 it was purported to provide constant, peakless insulin release following once- or twice-daily administration, thus leading to fewer hypoglycaemic episodes while providing metabolic control equivalent to that achieved with NPH human basal insulin. Aims: To investigate the indications used for prescription of a new drug and its clinical effects on glycosylated haemoglobin (HbA1c) levels, perceived hypoglycaemic events and patient satisfaction. Methods: The Diabetes Treatment Satisfaction Questionnaire (Status Version, DTSQ-s), which measures satisfaction with treatment regimen, and perceived frequency of hyperglycaemia and hypoglycemia, was circulated to all living patients who had ever started treatment with insulin glargine at the Department of Endocrinology at Malmö University Hospital. Medical records of 913 patients were assessed for HbA1c levels at 0 and 12 months after starting insulin glargine therapy. Results: Completed questionnaires were returned by 615 of 960 patients (64%) who had ever started insulin glargine. The main indications for starting treatment were physicians' or nurses' initiatives, desire for fewer fluctuations and improved metabolic control. HbA1c levels fell by 0.41% for patients with type 1 diabetes and by 0.68% for those with type 2 diabetes. The mean DTSQ-s score was 28.45 for satisfaction, whereas the mean perceived hypoglycaemic/hyperglycaemic events score was 3. Conclusion: Treatment satisfaction was very high and perceived frequency of hypoglycaemia/hyperglycaemia was very low. The indications for treatment of insulin glargine are being followed in accordance with national recommendations..
DOI http://dx.doi.org/10.1002/edn.127 (link to publisher's fulltext)
Publisher Wiley-Blackwell
Host/Issue European Diabetes Nursing;1
Volume 6
ISSN 1551-7853
Pages 17-22
Language eng (iso)
Subject(s) hyperglycaemia
diabetes treatment satisfaction
insulin glargine
patient perspective
hypoglycaemia
Medicine
Research Subject Categories::MEDICINE
Handle http://hdl.handle.net/2043/14303 (link to this page)

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