Importance of Ca(2+) modifications for osseointegration of smooth and moderately rough anodized titanium implants - a removal torque and histological evaluation in rabbit

DSpace Repository

Importance of Ca(2+) modifications for osseointegration of smooth and moderately rough anodized titanium implants - a removal torque and histological evaluation in rabbit

Show full item record

Files for download

Find Full text There are no files associated with this item.

Facebook

Simple item record

Publication Article, peer reviewed scientific
Title Importance of Ca(2+) modifications for osseointegration of smooth and moderately rough anodized titanium implants - a removal torque and histological evaluation in rabbit
Author(s) Fröjd, Victoria ; Wennerberg, Ann ; Franke Stenport, Victoria
Date 2012
English abstract
BACKGROUND: Incorporation of Ca(2+) into the titania of anodized titanium surfaces has been found to enhance osseointegration. It provides a stable surface when the ions are incorporated into the oxide layer during the anodizing process. The Ca(2+) may suggestively be prominent sites for mineral induction, attract proteins, and catalyze intracellular cascades. PURPOSE: The aim of the present study was to evaluate the osseointegration of smooth (S(a) < 0.5 µm) and moderately rough (S(a) 1.0-2.0 µm) commercially pure titanium implants, with and without Ca(2+) , in order to reflect on the importance of surface chemistry in relation to topography. MATERIALS AND METHODS: Anodized implants with (OxCa) or without Ca(2+) (Ox), blasted implants (Bl), and blasted anodized implants, with (BlOxCa) or without Ca(2+) (BlOx), were inserted in rabbit femur and tibia. The implant surfaces were characterized using interferometry, scanning electron microscopy, and X-ray photoelectron spectroscopy prior to implant installation. Removal torque (RTQ) measurements were executed on all implants after a healing period of 12 weeks. The implants were, thereafter, removed en bloc with surrounding tissues and prepared for histological evaluations. RESULTS: RTQ measurements of tibial implants revealed significantly higher values for BlOxCa implants (90.7 ± 23.3 Ncm) compared to OxCa (64.6 ± 18.2 Ncm) and BlOx implants (69.7 ± 17.5 Ncm) (p = 0.029). Ca(2+) modification of smooth implants placed in the femur did not reveal any differences. CONCLUSION: Ca(2+) modification of smooth implants resulted in similar interfacial shear strength as moderately rough implants and Ca(2+) modification of moderately rough implants demonstrated the significantly strongest interfacial shear strength when placed in rabbit tibia. This possibly demonstrated surface chemistry compensating for lesser roughness.
DOI http://dx.doi.org/10.1111/j.1708-8208.2010.00315.x (link to publisher's fulltext)
Publisher Wiley
Host/Issue Clinical Implant Dental Related Research;5
Volume 14
ISSN 1523-0899
Pages 737-745
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/14719 (link to this page)

This item appears in the following Collection(s)

Show full item record

Search


Browse

My Account

Statistics