Accelerated photo-induced hydrophilicity promotes osseointegration : an animal study

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Accelerated photo-induced hydrophilicity promotes osseointegration : an animal study

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Publication Article, peer reviewed scientific
Title Accelerated photo-induced hydrophilicity promotes osseointegration : an animal study
Author(s) Jimbo, Ryo ; Ono, D ; Hirakawa, Y ; Odatsu, T ; Tanaka, T ; Sawase, Takashi
Date 2011
English abstract
BACKGROUND: In the previous in vitro study, fluoride-modified, anodized porous titanium was proven to have enhanced its photo-induced hydrophilicity, which induced the hyperactivation of initial cell response. PURPOSE: The purpose of the present study was to investigate in vivo bone apposition during the early stages of osseointegration in rabbit tibiae. MATERIALS AND METHODS: Anodized porous titanium implants (TiU, TiUnite®, Nobel Biocare AB, Göteborg, Sweden) were modified with 0.175 wt% ammonium hydrogen fluoride solution (NH(4) F-HF(2) ). Twenty-four hours prior to the experiments, the surface-modified implants were ultraviolet-irradiated (modTiU). Blinded and unpackaged TiU implants were used as controls. Thereafter, the implants were placed in the rabbit tibial metaphyses and histomorphometrically analyzed at 2 and 6 weeks after insertion. RESULTS: ModTiU demonstrated a significantly greater degree of bone-to-metal contact than TiU after 2 and 6 weeks of healing. CONCLUSION: The results proved that the enhanced photo-induced hydrophilicity of the NH(4) F-HF(2) -modified anodized implants promoted bone apposition during the early stages of osseointegration.
DOI http://dx.doi.org/10.1111/j.1708-8208.2009.00179.x (link to publisher's fulltext)
Publisher Wiley
Host/Issue Clinical Implant Dentistry Related Research;1
Volume 13
ISSN 1708-8208
Pages 79-85
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/16382 (link to this page)

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