The influence of nano hydroxyapatite coating on osseointegration after extended healing periods

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The influence of nano hydroxyapatite coating on osseointegration after extended healing periods

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Publication Article, peer reviewed scientific
Title The influence of nano hydroxyapatite coating on osseointegration after extended healing periods
Author(s) Bryington, Matthew S ; Hayashi, Mariko ; Kozai, Yusuke ; Vandeweghe, Stefan ; Andersson, Martin ; Wennerberg, Ann ; Jimbo, Ryo
Date 2013
English abstract
OBJECTIVE: Studies observing early wound healing periods around dental implants demonstrate an implants ability to enhance osseointegration, the bone-implant interactions for extended healing periods though have not been thoroughly studied. METHODS: Twenty threaded titanium alloy (Ti6Al4V, Grade 5) implants were inserted bilaterally, half prepared to impart stable hydroxyapatite nanoparticles onto a sand blasted and acid etched surface (HA) and half with a non-coated control surface with only heat treatment (HT), into eighteen rabbit femurs. At 12 weeks, the bone-implant blocks were retrieved for micro computed tomography (μCT), histologic processing and histomorphometric evaluation. RESULTS: The bone-to-implant contact for the entire threaded portion of the implant revealed 57.1% (21.0) for the HT group and 38.8% (17.7) for the HA group with a total bone area within the threads 72.5% (13.9) (HT) and 59.7% (12.5) (HA). The 3D reconstructed μCT image corresponded to the histomorphometric results. SIGNIFICANCE: It is suggested that multiple factors such as the change in topography and chemistry may have influenced the outcomes.
DOI http://dx.doi.org/10.1016/j.dental.2013.02.004 (link to publisher's fulltext)
Publisher Elsevier
Host/Issue Dental Materials;5
Volume 29
ISSN 0109-5641
Pages 514–520
Language eng (iso)
Subject(s) Dental implants
Osseointegration
Hydroxyapatite
Histomorphometry
Nanotopography
Implant surface
Rabbit study
Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/16385 (link to this page)

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