Effect of experimental tooth clenching on the release of β-endorphin

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Effect of experimental tooth clenching on the release of β-endorphin

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Publication Article, peer reviewed scientific
Title Effect of experimental tooth clenching on the release of β-endorphin
Author(s) Dawson, Andreas ; Ljunggren, Lennart ; Ernberg, Malin ; Svensson, Peter ; List, Thomas
Date 2014
English abstract
AIMS: To investigate the association between experimental tooth clenching and the release of β-endorphin in patients with myofascial temporomandibular disorders (M-TMD) and healthy subjects. METHODS: Fifteen M-TMD patients and 15 healthy subjects were included and assigned an experimental tooth-clenching task. Venous blood was collected and pain intensity was noted on a visual analog scale. The masseter pressure pain threshold (PPT) was assessed 2 hours before the clenching task and immediately after. A mixed-model analysis of variance was used for statistical analyses. RESULTS: Significant main effects for time and group were observed for pain intensity and PPT, with significantly lower mean values of pain intensity (P < .001) and PPT (P < .01) after the clenching task compared with baseline. M-TMD patients had significantly higher pain intensity (P < .001) and significantly lower PPT (P < .05) than healthy subjects. No significant time or group effects were observed for the level of β-endorphin. Neither pain intensity nor PPT correlated significantly with β-endorphin levels. CONCLUSION: This experimental tooth-clenching task was not associated with significant alterations in β-endorphin levels over time, but with mechanical hyperalgesia and low to moderate levels of pain in healthy subjects and M-TMD patients, respectively. More research is required to understand the role of the β-endorphinergic system in the etiology of M-TMD
DOI http://dx.doi.org/10.11607/ofph.1210 (link to publisher's fulltext)
Publisher Quintessence
Host/Issue Journal of oral & facial pain and headache;2
Volume 28
ISSN 2333-0384
Pages 159-164
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/17999 (link to this page)

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