Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: A study in the rabbit tibia

DSpace Repository

Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: A study in the rabbit tibia

Show full item record

Files for download

Facebook

Simple item record

Publication Article, peer reviewed scientific
Title Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants: A study in the rabbit tibia
Author(s) Johansson, Pär ; Jimbo, Ryo ; Kjellin, Per ; Currie, Fredrik ; Chrcanovic, Bruno ; Wennerberg, Ann
Date 2014
English abstract
Polyether ether ketone (PEEK) is today frequently used as a biomaterial in different medical operations due to its excellent mechanical and chemical properties. However, the untreated surface of PEEK is bioinert and hydrophobic, and it does not osseointegrate in its pure form. The aim of this study was to evaluate a unique nano-modified surface of PEEK with respect to osseointegration. Forty-eight threaded, non-cutting PEEK implants were inserted bilaterally in the tibia of 24 rabbits. Half of the implants (n=24) were coated with nanocrystalline hydroxyapatite (test) and the remaining implants (n=24) were left uncoated (control). Half of the animals (n=12) were euthanized after 3 weeks of healing and the remaining (n=12) after 12 weeks. The implant retention was measured with a removal torque apparatus. Surface analysis was performed with interferometry, scanning electron microscopy, and X-ray photon spectroscopy to relate the removal torque to the applied surface. The test implants revealed a significantly higher retention after 3 weeks (P=0.05) and 12 weeks (P=0.028) compared to controls. The result of the present study proves that the addition of nanocrystalline hydroxyapatite coating to PEEK surfaces significantly increases its removal torque and biocompatibility.
DOI http://dx.doi.org/10.2147/IJN.S60387 (link to publisher's fulltext)
Publisher Dove Press
Host/Issue International Journal of Nanomedicine;
Volume 9
ISSN 1178-2013
Pages 3903-3911
Language eng (iso)
Subject(s) Hydroxyapatite
Nanotopography
Polyether ether ketone
Removal torque
Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/18025 (link to this page)

This item appears in the following Collection(s)

Show full item record

Search


Browse

My Account

Statistics