Dental implants in irradiated versus non-irradiated patients : a meta-analysis

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Dental implants in irradiated versus non-irradiated patients : a meta-analysis

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Publication Article, review peer-reviewed scientific
Title Dental implants in irradiated versus non-irradiated patients : a meta-analysis
Author(s) Chrcanovic, Bruno ; Albrektsson, Tomas ; Wennerberg, Ann
Date 2015
English abstract
Background/Methods. The purpose of the present meta-analysis was to test the null hypothesis of no difference in dental implant failure rates, postoperative infection, and marginal bone loss for patients being rehabilitated by dental implants and being previously irradiated in the head and neck region versus non-irradiated patients, against the alternative hypothesis of a difference. Results/Conclusion. The study suggests that irradiation negatively affects the survival of implants, as well as the difference in implant location (maxilla vs. mandible), but there is no statistically significant difference in survival when implants are inserted before or after 12 months after radiotherapy. The study failed to support the effectiveness of hyperbaric oxygen therapy in irradiated patients. It was observed a tendency to lower survival rates of implants inserted in the patients submitted to higher irradiation doses. The results should be interpreted with caution due to the presence of uncontrolled confounding factors in the included studies.
DOI http://dx.doi.org/10.1002/hed.23875 (link to publisher's fulltext)
Publisher Wiley
Host/Issue Head & Neck;
ISSN 1097-0347
Language eng (iso)
Subject(s) Dental implants
Radiotherapy
Infection
Marginal bone loss
Meta-analysis
Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/18139 (link to this page)

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