Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants : a study in the rabbit tibia

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Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants : a study in the rabbit tibia

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Publication Article, peer reviewed scientific
Title Biomechanical evaluation and surface characterization of a nano-modified surface on PEEK implants : a study in the rabbit tibia
Author(s) Johansson, Pär ; Jimbo, Ryo ; Kjellin, Per ; Currie, Fredrik ; Ramos Chrcanovic, Bruno ; Wennerberg, Ann
Date 2014
English abstract
Polyether ether ketone (PEEK) is today frequently used as a biomaterial in different medical operations due to its excellent mechanical and chemical properties. However, the untreated surface of PEEK is bio-inert, hydrophobic and does not osseointegrate in its pure form. The aim of this study was to evaluate a unique nano modified surface of PEEK with respect to osseointegration. Forty-eight threaded, non-cutting PEEK implants were inserted bilaterally in the tibia of 24 rabbits. Half of the implants (n = 24) were coated with nanocrystalline hydroxyapatite (test) and the remaining implants (n = 24) were left uncoated (control). Half of the animals (n = 12) were euthanized after 3 weeks of healing and the remaining (n = 12) after 12 weeks. The implant retention was measured with a removal torque apparatus. Surface analysis was performed with interferometry, scanning electron microscopy and X-ray photon spectroscopy to relate the removal torque to the applied surface. The test implants revealed a significantly higher retention after 3 weeks (p-value = 0.05) and 12 weeks (p-value = 0.028) compared to controls. The result of the present study proves that the addition of nanocrystalline HA coating to PEEK surfaces significantly increased its removal torque and biocompability.
DOI http://dx.doi.org/10.2147/IJN.S60387 (link to publisher's fulltext)
Publisher Dove Medical Press
Host/Issue International journal of nanomedicine;
Volume 9
ISSN 1178-2013
Pages 3903-3911
Language eng (iso)
Subject(s) PEEK
polyether ether ketone
hydroxyapatite
removal torque
nanotopography
Humanities/Social Sciences
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/18156 (link to this page)

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