Estimates of sensitivity and specificity of electric pulp testing depend on pulp disease spectrum : a modelling study

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Estimates of sensitivity and specificity of electric pulp testing depend on pulp disease spectrum : a modelling study

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Publication Article, peer reviewed scientific
Title Estimates of sensitivity and specificity of electric pulp testing depend on pulp disease spectrum : a modelling study
Author(s) Mejare, Ingegerd ; Bergenholtz, G. ; Petersson, Kerstin ; Tranaeus, S.
Date 2015
English abstract
Aim To demonstrate how the spectrum of diseased pulps may influence sensitivity and specificity in diagnostic studies on pulp status. Methodology An original sample from a previous study consisting of 59 teeth scheduled for root canal treatment was used where the relationship between the response to electric pulp testing and the visual status of the pulp was evaluated. To alter the spectrum of diseased pulps, a hypothetical sample of asymptomatic teeth with deep caries lesions was added to the original sample. Sensitivity and specificity were then compared for the two samples. Results In the original sample of 59 teeth, sensitivity was 72% and specificity 90%. When the spectrum of diseased pulps was altered, sensitivity decreased to 67% and specificity increased to 97%. The change in disease spectrum also decreased the prevalence of necrotic pulps. Conclusions The spectrum of diseased pulps included in a diagnostic study on the accuracy of electric pulp testing, and indirectly also disease prevalence (here pulp necrosis), influences estimates of sensitivity and specificity. This implies that estimates of diagnostic accuracy from one study with a particular tooth population spectrum may not apply to another tooth population with a different disease spectrum.
DOI http://dx.doi.org/10.1111/iej.12277 (link to publisher's fulltext)
Publisher Wiley
Host/Issue International Endodontic Journal;1
Volume 48
ISSN 0143-2885
Pages 74-78
Language eng (iso)
Subject(s) diagnosis
diagnostic accuracy
endodontic treatment
endodontics
pulp
necrosis
Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/19635 (link to this page)

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