A randomised study of NPWT closure versus alginate dressings in peri-vascular groin infections : quality of life, pain and cost

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A randomised study of NPWT closure versus alginate dressings in peri-vascular groin infections : quality of life, pain and cost

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Publication Article, peer reviewed scientific
Title A randomised study of NPWT closure versus alginate dressings in peri-vascular groin infections : quality of life, pain and cost
Author(s) Monsen, Christina ; Acosta, Stefan ; Mani, Kevin ; Wann-Hansson, Christine
Date 2015
English abstract
OBJECTIVE: The aim of this study was to compare the vacuum assisted wound closure (VAC) system (negative pressure wound therapy; NPWT) and alginate wound dressings in terms of quality of life (QoL), pain resource use and cost in patients with deep peri-vascular groin infection after vascular surgery. METHOD: Patients with deep peri-vascular groin infection (Szilagyi grade III) were included and randomised to NPWT or alginate therapy. EuroQol 5D (EQ-5D) and brief pain inventory (BPI) were used to evaluate QoL and pain, respectively. RESULTS: Wound healing time until complete skin epithelialisation was shorter in the NPWT (n=9) compared to the alginate group (n=7), median 57 and 104 days, respectively (p=0.026). No difference was recorded in QoL and pain between the groups at study start and the second assessment. QoL analysis within groups between time points, showed that patients in NPWT groups improved in EQ-5D domains, 'self-care' (p= 0.034), 'usual activities' (p=0.046); EQ-5D index value (p=0.046) and EQ-VAS (p=0.028). Patients in the NPWT group reported significantly less pain 'affecting their relations with other people' and 'sleep' between time points. The NPWT group had significantly fewer dressing changes compared to the alginate group (p<0.001). The median frequency of wound dressing changes outside hospital was 20 (IQR 6-29) in the NPWT group (n=9), compared to 48 (IQR 42-77) in the alginate group (n=8; p=0.004). The saved personnel time for wound care in the first week for the NPWT group, compared with the alginate group, was 4.5 hours per week per nurse. The total hospitalised care cost was 83-87% of the total cost in both groups. CONCLUSION: NPWT therapy in patients with deep peri-vascular groin infection can be regarded as the dominant strategy due to improved clinical outcome with equal cost and quality of life measures.
DOI http://dx.doi.org/10.12968/jowc.2015.24.6.252 (link to publisher's fulltext)
Publisher MA Healthcare
Host/Issue Journal of Wound Care;6
Volume 24
ISSN 0969-0700
Pages 252-258
Language eng (iso)
Subject(s) Cost
Groin infection
Negative pressure wound therapy
Pain
Quality of life
Medicine
Research Subject Categories::MEDICINE
Handle http://hdl.handle.net/2043/19860 (link to this page)

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