Intraoral Lubrication of PRP-1, Statherin and Mucin as Studied by AFM

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Intraoral Lubrication of PRP-1, Statherin and Mucin as Studied by AFM

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Publication Article, peer reviewed scientific
Title Intraoral Lubrication of PRP-1, Statherin and Mucin as Studied by AFM
Author(s) Hahn Berg, Cecilia I ; Lindh, Liselott ; Arnebrant, Thomas
Date 2004
English abstract
The aim of this paper was to elucidate the mechanisms behind salivary lubrication with special emphasis on the lubricity of three key components of the pellicle, viz human acidic proline-rich protein 1 (PRP-1), human statherin and bovine submaxillary mucin (BSM). The lubricating properties of the proteins have been assessed by means of colloidal probe atomic force microscopy, and are discussed in relation to their adsorption behaviour. To various extents, the proteins investigated all showed a lubricating effect when adsorbed to silica surfaces. For comparable concentrations, PRP-1 was found to have a more pronounced lubricating effect than BSM, which in turn showed a higher lubricity than statherin. The relative lubricity is in accordance with previously reported relative adsorbed amounts of the three proteins, within the investigated concentration interval. It is concluded that PRP-1 has the highest lubricating capacity as a pure fraction among the preparations investigated, and that the lubricating effect of PRP-1 as a pure fraction is notably large as compared to the lubricity of human whole saliva.
DOI http://dx.doi.org/10.1080/08927010310001639082 (link to publisher's fulltext)
Publisher Taylor & Francis
Host/Issue Biofouling;1
Volume 20
ISSN 0892-7014
Pages 65-70
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::NATURAL SCIENCES::Chemistry::Physical chemistry::Surface and colloid chemistry Research Subject
Handle http://hdl.handle.net/2043/2765 (link to this page)

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