Clinical Outcome Observed in Subjects with Recurrent Periodontal Disease Following Local Treatment with 25% Metronidazole Gel.

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Clinical Outcome Observed in Subjects with Recurrent Periodontal Disease Following Local Treatment with 25% Metronidazole Gel.

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Publication Article, other scientific
Title Clinical Outcome Observed in Subjects with Recurrent Periodontal Disease Following Local Treatment with 25% Metronidazole Gel.
Author(s) Jansson, Henrik ; Bratthall, Douglas ; Söderholm, Gunnar
Date 2003
English abstract
BACKGROUND: The aim of this study was to evaluate the clinical outcome in patients with recurrent periodontal disease following treatment with 25% metronidazole gel. METHODS: Twenty subjects in a maintenance care program but with recurrent periodontal disease participated. Three months after scaling and root planing, a total of 40 sites, 2 in each patient, with probing depth > or = 5 mm were selected. One site randomly selected was treated with metronidazole gel (test) and the other site with a placebo gel (control). Baseline and follow-up measurements included plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL). RESULTS: There were no statistically significant differences in PI, GI, BOP, PD, or CAL between test and control sites. CONCLUSION: This study showed that local treatment with 25% metronidazole gel did not seem to influence the clinical healing in this group of subjects with recurrent periodontal disease.
DOI http://dx.doi.org/10.1902/jop.2003.74.3.372 (link to publisher's fulltext)
Host/Issue Journal of periodontology
Volume 74
ISSN 0022-3492
Pages 372-377
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY::Periodontology
Handle http://hdl.handle.net/2043/3027 (link to this page)

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