Human Saliva Forms a Complex Film Structure on Alumina Surfaces

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Human Saliva Forms a Complex Film Structure on Alumina Surfaces

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Publication Article, peer reviewed scientific
Title Human Saliva Forms a Complex Film Structure on Alumina Surfaces
Author(s) Cardenas, Marité ; Lindh, Liselott ; Arnebrant, Thomas ; Thomas, Robert ; Fragnetto, Giovanna ; Rennie, Adrian
Date 2007
English abstract
Films formed from saliva on surfaces are important for maintenance of oral health and integrity by protection against chemical and/or biological agents. The aim of the present study was to investigate adsorbed amounts, thickness and the structure of films formed from human whole saliva on alumina surfaces by means of in situ ellipsometry, neutron reflectivity and atomic force microscopy. Alumina (Al2O3, synthetic sapphire) is a relevant and interesting substrate for saliva adsorption studies as it has an isoelectric point close to that of tooth enamel. The results showed that saliva adsorbs rapidly on alumina. The film could be modelled in two layers: an inner and dense thin region which forms a uniform layer, and an outer, more diffuse and thicker region that protrudes towards the bulk of the solution. The film morphology described a uniformly covering dense layer and a second outer layer containing polydisperse adsorbed macromolecules or aggregates.
DOI http://dx.doi.org/10.1021/bm060492t (link to publisher's fulltext)
Publisher American Chemical Society
Host/Issue Biomacromolecules;1
Volume 8
ISSN 1525-7797
Pages 65-69
Language eng (iso)
Subject(s) Sciences
Research Subject Categories::NATURAL SCIENCES::Chemistry::Physical chemistry::Surface and colloid chemistry
Handle http://hdl.handle.net/2043/4475 (link to this page)

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