Effects on blood pressure after treatment of obstructive sleep apnea with an oral appliance with mandibular advancement, a 3 year follow-up.

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Effects on blood pressure after treatment of obstructive sleep apnea with an oral appliance with mandibular advancement, a 3 year follow-up.

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Publication Conference Paper, other
Title Effects on blood pressure after treatment of obstructive sleep apnea with an oral appliance with mandibular advancement, a 3 year follow-up.
Author(s) Tegelberg, Å ; Andrén, A
Date 2007
English abstract
The study purpose was to investigate if rduction of obstructive sleep apnea with oral appliance therapy (AO)affects blood pressure (BP) in hypertensive patients in a short-term and long-term perspective. Material and methods: Twenty-nine consecutive patients with verified obstructive sleep apnea (OSA);defined as apnea index (AI) <5 and/or panea-hypoponea index (AHI) <10/hours, received as a treatment an OA with mandibular advancement. The reference BP was measured at 3 study visits; before treatment, after 3 months and after 3 yrs of treatment, respectively. The CP was measured twice at those visits with an automatic unit and the second value was registered as the CP of the visit. The treatment effect of OSA was measured after 3 months use by are repeated somnographic registration wearing the OA. At this short-term evaluation after 3 months the patients were asked about the compliance and the frequency of OA use nights/week. At the long-term follow up after 3 years use of OA the patients answered questions about altering in and hypotensive medication, frequency in use of OA (nights/week), weight gain or loss and a self-report of general well-being. A complete response to treatment was considered as success when a normalization of nightly breathing occurred, defined as AHI<10. Results: Between baseline and the short-term evaluation 4 patients changed treatment. A complete treatment response of OSA was achieved in 25 of 29 patients. The remaining 25 patients were called for a long-term follow-up after 3 years. Three patients were unable to participate. At the 3 years follow-up the remaining 22 treated patients had a statistically significant reduction for the sustolic BP of -15.4mm Hg and for the diastolic BP of -10.3mm Hg. This significance was received between baseline and the short-term evaluation (p<0.001), and remained at the long-term follow-up. All 22 patients reported a good general well being after 3 years of treatment. Conclusion: OA therapy reduced blood pressure in both short-term and long-term perspectives in patients with OSA and hypertension.
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY
Note Odontologisk Riksstämma 2007, Sverige
Handle http://hdl.handle.net/2043/5157 (link to this page)

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