Automated osteoporosis risk assessment by dentists: a new pathway to diagnosis

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Automated osteoporosis risk assessment by dentists: a new pathway to diagnosis

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Publication Article, peer reviewed scientific
Title Automated osteoporosis risk assessment by dentists: a new pathway to diagnosis
Author(s) Devlin, Hugh ; Allen, Philip D ; Graham, Jim ; Jacobs, Reinhilde ; Karayianni, Kety ; Lindh, Christina ; van der Stelt, Paul F ; Harrison, Elizabeth ; Adams, Judith ; Pavitt, Susan ; Horner, Keith
Date 2007
English abstract
General dental practitioners use a vast amount of panoramic radiography in their routine clinical work, but valuable information about patients' osteoporotic status is not collected. There are many reasons for this, but one of the prime reasons must be the disruption involved in clinical routine with lengthy manual radiographic assessment. We have developed computer software, based on active shape modeling that will automatically detect the mandibular cortex on panoramic radiographs, and then measure its width. Automatic or semi-automatic measurement of the cortical width will indicate the osteoporotic risk of the patient. The aim of our work was to assess the computer search technique's ability to measure the mandibular cortical width and to assess its potential for detection of osteoporosis of the hip, spine and femoral neck. Mandibular cortical width was measured using the manually initialized (semi-automatic) method and, when assessed for diagnosing osteoporosis at one of the three measurement sites, gave an area under the ROC curve (A(z))=0.816 (95% CI=0.784 to 0.845) and for the automatically initialized searches, A(z)=0.759 (95% CI=0.724 to 0.791). The difference between areas=0.057 (95% Confidence interval=0.025 to 0.089), p<0.0001. For diagnosing osteoporosis at the femoral neck, mandibular cortical width derived from the manually initialized fit gave an area under the ROC curve (A(z))=0.835 (95% CI=0.805 to 0.863) and for the automatically initialized searches A(z)=0.805 (95% CI=0.773 to 0.835). The difference in A(z) values between active shape modeling search methods=0.030 (95% CI=-0.010 to 0.070), and this was not significant, p=0.138. We concluded that measurement of mandibular cortical width using active shape modeling is capable of diagnosing skeletal osteoporosis with good diagnostic ability and repeatability. PMID: 17188590 [PubMed - indexed for MEDLINE]
DOI http://dx.doi.org/10.1016/j.bone.2006.10.024 (link to publisher's fulltext.)
Host/Issue Bone;4
Volume 40
ISSN 8756-3282
Pages 835-42
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY::Radiological research
Handle http://hdl.handle.net/2043/5533 (link to this page)

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