The mandibular cortex on radiographs as a tool for osteoporosis risk assessment: the OSTEODENT Project

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The mandibular cortex on radiographs as a tool for osteoporosis risk assessment: the OSTEODENT Project

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Publication Article, peer reviewed scientific
Title The mandibular cortex on radiographs as a tool for osteoporosis risk assessment: the OSTEODENT Project
Author(s) Horner, Keith ; Karayianni, Kety ; Mitsea, Anastasia ; Berkas, Leonidas ; Mastoris, Michael ; Jacobs, Reinhilde ; Lindh, Christina ; van der Stelt, Paul ; Marjanovic, Elizabeth ; Adams, Judith ; Pavitt, Susan ; Devlin, Hugh
Date 2007
English abstract
The aim of this study was to measure the accuracy of porosity of the mandibular cortex on dental panoramic radiographs (DPRs) in diagnosis of osteoporosis, alone and in combination with a clinical risk index. Six hundred seventy-one women (45-70yr) were recruited in the study, and dual-energy X-ray absorptiometry of the hip and lumbar spine was performed. A clinical index of osteoporosis risk (OSIRIS) and a DPR were obtained for each subject. The cortical appearance on the DPR was classified using the mandibular cortical index (MCI) by 5 observers. receiver operating characteristic (ROC) curve analysis was performed with calculation of area under the ROC curve (AUC) and sensitivity and specificity at various thresholds. Complete data were available for 653 subjects, of whom 21.6% had osteoporosis. The AUC for OSIRIS was 0.838. When used alone as the diagnostic test, MCI AUC for the 5 observers ranged from 0.560 to 0.670, significantly less than OSIRIS. Intraobserver and interobserver repeatability of MCI assessment was inconsistent. We conclude that MCI has limited value for osteoporosis diagnosis, being most appropriate as a method of fortuitous case-finding. PMID: 17449308 [PubMed - in process]
DOI http://dx.doi.org/10.1016/j.jocd.2007.02.004 (link to publisher's fulltext)
Host/Issue Journal of clinical densitometry;2
Volume 10
ISSN 1094-6950
Pages 138-46
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY::Radiological research
Handle http://hdl.handle.net/2043/5536 (link to this page)

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