Health-related quality of life in patients with pharyngeal carcinoma: a five-year follow-up

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Health-related quality of life in patients with pharyngeal carcinoma: a five-year follow-up

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Publication Article, peer reviewed scientific
Title Health-related quality of life in patients with pharyngeal carcinoma: a five-year follow-up
Author(s) Nordgren, Mats ; Jannert, Magnus ; Boysen, Morten ; Ahlner Elmqvist, Marianne ; Silander, Ewa ; Bjordal, Kristin ; Hammerlid, Eva
Date 2006
English abstract
PURPOSE: The purpose was to evaluate the health-related quality of life (HRQL) of patients with pharyngeal carcinoma at diagnosis and after 1 and 5 years in relation to tumor location and treatment modality in a prospective multicenter study. METHODS: Eighty-nine patients with pharyngeal carcinoma (mean age, 60.0 years; 76% men) were evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Cancer Module (EORTC QLQ-H&N35). RESULTS: Problems with dry mouth and teeth became worse between diagnosis and the 5-year follow-up. Problems with thick secretions and teeth increased between 1 and 5 years. The HRQL at diagnosis was associated with survival. Patients with oropharyngeal carcinoma reported better HRQL than patients with hypopharyngeal carcinoma. CONCLUSIONS: For patients with pharyngeal carcinoma, the HRQL at diagnosis seems to be an important factor for the prognosis of both HRQL over time and survival. Treatment of pharyngeal carcinoma often results in long-term side effects such as dry mouth, problems with teeth, and thick secretions.
DOI http://dx.doi.org/doi:10.1002/hed.20334 (link to publisher's fulltext)
Publisher Wiley
Host/Issue Head and Neck;4
Volume 28
ISSN 1043-3074
Pages 339-49
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::MEDICINE
Handle http://hdl.handle.net/2043/7170 (link to this page)

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