Quality of life in oral carcinoma: a 5-year prospective study

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Quality of life in oral carcinoma: a 5-year prospective study

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Publication Article, peer reviewed scientific
Title Quality of life in oral carcinoma: a 5-year prospective study
Author(s) Nordgren, Mats ; Hammerlid, Eva ; Bjordal, Kristin ; Ahlner Elmqvist, Marianne ; Boysen, Morten ; Jannert, Magnus
Date 2008
English abstract
BACKGROUND: We conducted this prospective longitudinal multicenter study to evaluate the health-related quality of life (HRQL) of patients with oral carcinoma at diagnosis, and after 1 and 5 years in relation to tumour location and treatment modality. METHODS: One hundred twenty-two patients (mean age, 61; 62% males) with oral carcinoma were evaluated with standardized HRQL questionnaires, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core30 (EORTC QLQ-C30) and the EORTC Head and Neck Cancer Module (EORTC QLQ-H&N35). RESULTS: Problems with teeth, dry mouth, and sticky saliva got worse between diagnosis and 5 years after diagnosis. Problems with dry mouth remained a problem between 1 and 5 years after diagnosis, except for the patients treated with surgery only. This group had fewer problems over time compared with patients receiving other treatment regimes. Survivors reported better HRQL than the nonsurvivors at diagnosis and at the 1-year follow-up. HRQL at diagnosis was associated with survival. CONCLUSIONS: HRQL at diagnosis for patients with oral carcinoma seems to be an important factor for the prognosis of both HRQL over time and survival. Treatment of oral carcinoma often results in long-term side effects such as dry mouth, problems with teeth, and sticky saliva.
DOI http://dx.doi.org/10.1002/hed.20735 (link to publisher's fulltext)
Publisher Wiley: InterScience
Host/Issue Head and Neck;4
Volume 30
ISSN 1043-3074
Pages 461-70
Language eng (iso)
Subject(s) longitudinal HRQL
EORTC QLQ-C30
EORTC QLQ-H&N35
oral carcinoma
Medicine
Research Subject Categories::MEDICINE
Handle http://hdl.handle.net/2043/7604 (link to this page)

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