Bone formation after implantation of autolysed antigen extracted allogeneic bone in ovariectomized rabbits.

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Bone formation after implantation of autolysed antigen extracted allogeneic bone in ovariectomized rabbits.

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Publication Article, peer reviewed scientific
Title Bone formation after implantation of autolysed antigen extracted allogeneic bone in ovariectomized rabbits.
Author(s) Öberg, Sven ; Johansson, C ; Rosenquist, Jan
Date 2003
English abstract
This study was undertaken to evaluate the bone formation response to AAA bone in healthy and oestrogen deficient animals. Seventeen young healthy New Zealand female rabbits were used. Nine rabbits were subjected to ovariectomy and the remaining eight were sham-operated. Four weeks after ovariectomy standardized round cavities, 5mm in diameter, were made medially in the cortical part of each proximal tibia. To half of the cavities autolysed antigen-extracted al-logeneic AAA bone granules were added. After another 8 weeks the animals were sacrificed and sections of the tibial experimental areas were obtained. These were studied in light microscopy and the bone and non-bone areas were measured with computer support.The study showed that the addition of a bone inductive substance such as AAA bone enhances bone formation also in oestrogen deficient animals.
DOI http://dx.doi.org/10.1054/ijom.2003.0428 (link to publisher's fulltext)
Host/Issue International Journal of Oral and Maxillofacial Surgery;6
Volume 32
ISSN 0901-5027
Pages 628-32
Language eng (iso)
Subject(s) bone formation
AAA bone
bone defect
osteoporosis
ovariectomy
Medicine
Research Subject Categories::ODONTOLOGY
Handle http://hdl.handle.net/2043/7879 (link to this page)

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