Caries-preventive effect of fissure sealants: a systematic review.

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Caries-preventive effect of fissure sealants: a systematic review.

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Publication Article, review
Title Caries-preventive effect of fissure sealants: a systematic review.
Author(s) Mejàre, Ingegerd ; Lingström, Peter ; Petersson, Lars G ; Holm, Anna-Karin ; Twetman, Svante ; Källestål, Carina ; Nordenram, Gunilla ; Lagerlöf, Folke ; Söder, Birgitta ; Norlund, Anders ; Axelsson, Susanna ; Dahlgren, Helena
Date 2003
English abstract
The objectives of this study were to evaluate systematically the evi-dence of the caries-preventive effect of fissure sealing of occlusal tooth surfaces and to examine factors potentially modifying the effect. The search strategies included electronic databases, reference lists of arti-cles, and selected textbooks. Inclusion criteria were randomized or quasi-randomized clinical trials or controlled clinical trials comparing fissure sealing with no treatment or another preventive treatment in children up to 14 years of age at the start; the outcome measure was caries increment; the diagnostic criteria had been described; and the follow-up time was at least 2 years. Inclusion decisions were taken and grading of the studies was done independently by two of the authors. The main measure of effect was relative risk reduction. Thirteen stud-ies using resin-based or glass ionomer sealant materials were included in the final analysis. The results showed that most studies were per-formed during the 1970s and a single application had been utilized. The relative caries risk reduction pooled estimate of resin-based seal-ants on permanent 1st molars was 33% (relative risk = 0.67; CI = 0.55-0.83). The effect depended on retention of the sealant. In conclu-sion, the review suggests limited evidence that fissure sealing of 1st permanent molars with resin-based materials has a caries-preventive effect. The evidence is incomplete for permanent 2nd molars, premo-lars and primary molars and for glass ionomer cements. Overall, there remains a need for further trials of high quality, particularly in child populations with a low and a high caries risk, respectively.
Host/Issue Acta odontologica Scandinavica;6
Volume 61
ISSN 0001-6357
Pages 321-330
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY
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