Structural influence from Calcium Phosphate coatings and its possible effect on enhanced bone integration

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Structural influence from Calcium Phosphate coatings and its possible effect on enhanced bone integration

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Publication Article, peer reviewed scientific
Title Structural influence from Calcium Phosphate coatings and its possible effect on enhanced bone integration
Author(s) Wennerberg, Ann ; Albrektsson, Tomas
Date 2009
English abstract
Objective. The aim of this review was to summarize our present knowledge about calcium phosphate (CaP) coatings on implants with respect to their topographical appearance at micrometer as well as nanometer level and also the reported influence on bone healing. Material and methods . The PubMed database was used with the key words - surface roughness, CaP coating, implant, bone integration, clinical studies, experimental studies - used in different combinations. Only in vivo studies were taken into consideration. Conclusions. A significantly improved healing capacity associated with CaP-coated implants is often reported, but individual importance of the several modes of surface changes introduced, deliberately or not, is usually very difficult to interpret. Several studies claim this difference to be due to altered chemistry, but in many the result may equally well be dependent on the surface topography. The few studies that have been published indicate that nanometer structures have an impact on early bone healing. However, the optimal size and distribution of nanometer-sized particles or pores applied on implant surfaces is still unknown, as are the evaluation effects of micrometer roughness. Improved surface characterization is needed if we are to reveal effects dependent on isolated nanometer alterations.
DOI http://dx.doi.org/10.1080/00016350903188325 (link to publisher's fulltext)
Host/Issue Acta Odontologica Scandinavica;6
Volume 67
ISSN 0001-6357
Pages 333-340
Language eng (iso)
Subject(s) Medicine
Research Subject Categories::ODONTOLOGY::Oral prosthetics
Handle http://hdl.handle.net/2043/9010 (link to this page)

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